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These studies suggest that deficiencies in GH and IGF-I contribute to a functional decline in senescent rats, whereas augmentation of GH or IGF-I improves cognitive function, increases glucose utilization throughout the brain, increases cortical vascularity, and ameliorates age-related decline in hippocampal neurogenesis

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[DOI] [PubMed] [Google Scholar] 52.Horowitz M, Aroda VR, Han J, Hardy E, Rayner CK

The most frequently used protocol, established by Lippmann et al., involves co-differentiation of endothelial cells with neural cells followed by endothelial cell purification (Lippmann et al., 2012)

Vials stored in a standard freezer without desiccant packs show 1520% potency loss after 6 months