Common Side Effects: Injection site reactions (erythema, pruritus, pain) Arthralgia (joint pain) Peripheral edema (fluid retention) Myalgia (muscle pain) Pain in extremities Important Warnings: Contraindicated in active malignancy: GH/IGF-1 promote cell proliferation Contraindicated in pregnancy: Category X Glucose monitoring required: May affect glucose metabolism IGF-1 monitoring recommended: To assess response and safety Rare but Serious: Potential tumor growth stimulation Glucose intolerance/diabetes exacerbation Hypersensitivity reactions Fluid retention complications Regulatory Status United States: FDA approved (2010) for HIV-associated lipodystrophy
Zhang Y, Tang C, He Y, et al
Patients should specifically inform their doctor about diabetes medications (insulin, sulfonylureas, meglitinides), thyroid medications, anticoagulants, oral contraceptives, and any medications requiring precise timing or absorption
These annoying side-effects could potentially cause permanent damage to your teeth
Retail cash prices remain higher The pCPA-mandated price applies to public drug plans
Temporary Glow vs Progressive Improvement Ordinary creams may provide a temporary glow due to hydration or light-reflecting ingredients, but this effect fades quickly