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In this situation, it is often recommended to revert to a lower dose and re-escalate after four weeks

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CCH1: This Chinese medicine formulation includes Panax ginseng, ginger, Chinese licorice, baizhu, Aconitum carmichaelii, andRheum tanguticum

Continuous daily dosing beyond 72 hours may trigger c-Met receptor downregulation and internalization, reducing the compound's effectivenessa concern that favors intermittent protocols for extended research timelines

Observational cohort studies have reported lower risk of MACE, HF hospitalization, and serious kidney outcomes with combination therapy compared with either class alone [37]

Stewart, J