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Outcomes identified by the clinical expert that are important when assessing whether a patient is responding to treatment in clinical practice include: improvement in glycemic parameters, improvement in body weight with the attendant improvement in blood pressure and lipids, long-range improvement in microvascular and macrovascular events, and HRQoL

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10.1007/s00403-009-1019-6 186

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A preliminary study for evaluating the dose-dependent effect of d-Allulose for fat mass reduction in adult humans: A randomized, double-blind, placebo-controlled trial