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We estimated that with this sample size, the study would have 80% power to detect an absolute difference in the rate of improvement in ALT of 30 percentage points, with a two-sided type 1 error of 0.05

Water quality and detoxification through hydration are crucial considerations for those with the MTHFR mutation

37 , e3361 (2021)

Funding This research was funded by the National Natural Science Foundation of China (31872809) and the Natural Science Foundation of Shandong Province, China (ZR2020QC065)