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Diet-induced obesity models animal-model research has explored AOD-9604's effect on body composition, fat-mass markers, and energy expenditure in rodent obesity models

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"We can't say that GLP-1s are actually causing these symptoms," says Neil Sehgal, the study's first author and a doctoral student in CIS advised by Guntuku and Ungar

Researchers monitoring GI adverse events should collect data on meal patterns to differentiate compound-related GI effects from dietary confounders, particularly during the first 812 weeks of dose escalation when GI adverse events are most frequent