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found two patients with deletions in NPAP1, SNURF-SNRPN, and the SNORD genes, who exhibited major clinical signs of PWS, including obesity ( In summary, although data linking genotype and obesity in human studies is limited, these findings underscore the importance of taking a comprehensive approach to studying phenotypes throughout life

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Low zinc levels are associated with higher fasting blood sugar and HbA1c levels, indicating poorer glycemic control in type 2 diabetes mellitus [587,588,589]