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As of the time of writing, retatrutide has not been granted a marketing authorisation by the MHRA and is therefore not a licensed medicine in the United Kingdom

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5-Amino-1MQ is a substrate-mimetic inhibitor occupying the nicotinamide binding site, with a reported IC of 1.2 0.1 M (Neelakantan et al., J Med Chem, 2017)