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This reduction in hepatic CYP expression and activity resulted in elevated plasma drug concentrations and a higher incidence of adverse reactions (101)

Future perspectives in diabesity treatment: semaglutide, a glucagon-like peptide 1 receptor agonist (Review)

This includes environmental toxins, drugs, and metabolic waste products

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The complex was expressed and purified as described above for CDK11-cyclin L-SAP30BP, except that a nickel affinity purification step using Ni-NTA Superflow beads (Qiagen) was added before incubation with the Strep-Tactin Superflow resin, and the cleaved tags and TEV protease were removed by incubation with Ni-NTA Superflow beads before gel filtration

Aug 15 2012;19(11):1042-8