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Chronic pain is the most prevalent symptom of OA and has become a major factor affecting the physical and mental well-being of the elderly 2

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Conversely, several naturally produced antioxidant compounds (e.g., vitamins B12, C, K3, and catechin) were also shown to have a degree of anti-parasitic effect (Paveto et al., 2004

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Curcumin , the primary component in turmeric, fights inflammation and promotes heart health

Although prior studies have reported a positive association between serum B12 levels and increased risk of cancer or related mortality in general population and critically ill medical patients, attributing deleterious effects solely to excess B12 may be inappropriate [6, 29, 30]