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Additionally, it supports the activity of Superoxide Dismutase (SOD) , providing a model for studying cellular protection against oxidative stress

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Saffrons pharmacology (boosting dopamine/serotonin) means one should use caution if combining it with other serotonergic substances (like antidepressants such as SSRIs) to avoid any risk of serotonin overload

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The destructive factors include stomach hydrochloric acid (HCl), mucosal hypoperfusion, free oxygen radicals, ethanol, Helicobacter pylori and excessive ingestion of non-steroidal anti-inflammatory drugs (NSAIDs) that promote the gastric mucosal injury and contribute to gastric ulceration [3]