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Tirzepatide functions as both a glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor agonist

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And they lost more weight, too

But roughly 10 percent to 15 percent of patients in those trials were nonresponders who lost less than five percent of their body weight

That is no longer the mindset that we're trying to sort of put out there, but it is definitely multifaceted," she said, adding the piece gaining more attention now, in her view, is psychological support, particularly cognitive behavioral therapy and expanded mental health coverage that can address not just depression or anxiety as comorbidities, but also disordered eating patterns like binge eating

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