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Quick Answer: GLP-1 receptor agonists delay gastric emptying as a therapeutic mechanism that contributes to weight loss and glycemic control but can cause gastrointestinal symptoms and perioperative complications

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Reed RL, Pearlmutter L, Yochum K, Meredith KE, Mooradian AD

348 Similarly, in human chondrocytes stimulated by TNF, GLP-1 analogs (such as liraglutide) showed an anti-catabolic effect, reducing the mRNA expression of MMP-3, MMP-13, and ADAMTS5

J Proteome Res