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Topically yes

Toxins 16 (3), 117

benefits Delta sleep-inducing peptide (DSIP), which suppresses excess production of free radicals in the CNS and prevents neuron death during the bodys response to stress

Contamination happens easily and ruins entire vials

The standard regimen involves: Loading doses without neurological involvement : 1 mg intramuscularly three times a week for 2 weeks [3] [8] Loading doses with neurological involvement : 1 mg intramuscularly on alternate days until no further improvement [3] [8] Maintenance therapy : 1 mg every 23 months for life in cases of pernicious anaemia or irreversible malabsorption (every 2 months if neurological involvement) [3] [8] This aggressive approach aims to prevent irreversible neurological damage, though recovery of established neuropathy may be incomplete, particularly if treatment is delayed

Role of hydroxocobalamin in acute cyanide poisoning