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Long-term use should be discussed with a healthcare provider to ensure safety and identify any underlying issues requiring treatment
doi: 10.1002/anie.201909020 146 ChenSSunTZhengMXieZ
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Beyond deacetylation of histone proteins, HDACs also accept non-histone proteins as their substrates, finally affecting physiological and disease-related cellular processes, such as transcriptional machinery, DNA damage, signal transduction, protein folding, autophagy, and metabolism [60]
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