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Evidence-based efficacy of glutathione as an oral-lightening agent On review of literature, we could find only two studies that evaluated the efficacy of oral glutathione as a skin-lightening agent

J Biol Chem 250:14221426 Huang CS, Moore WR, Meister A (1988) On the active site thiol of gamma-glutamylcysteine synthetase: relationships to catalysis, inhibition, and regulation

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All about Glutathione Described as a master antioxidant, glutathione is synthesized in the liver from three amino acids, glycine, glutamic acid, and cysteine