Whether you're working with a regenerative peptide like BPC-157 or a growth hormone secretagogue like Ipamorelin, the fundamental process remains the same
Lancet Diabet Endocrinol 11:3341
GLP-1 agonists work primarily through gut-brain signaling and slowed gastric emptying
It is initiated by the activation of inflammasomes, which activate inflammatory caspases (such as caspase-1, -4, -5, and -11), leading to cleavage of Gasdermin D (GSDMD)
Once we start developing these drugs into longer lasting drugs that can be dosed once a week, that's when we get things like Victoza and Trulicity, and of course ultimately Ozempic and the latest drug is Mounjaro
For example, if you weigh 200 pounds, you should be drinking at least 100 ounces of water per day