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Together, these findings suggested the importance of GSH modulation during HIV infection, but the pathway involved to alter the GSH levels remained unknown

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doi: 10.1093/mutage/gew017 13 BoseS.SuescnA

Moreover, the weak parasitic load encountered in chubs could result in limited efflux compared with pollutant uptake (but see Possible Confounding Factors Parasitism induces a cascade of physiological and ecological changes (metabolism, foraging ecology, and social interaction), which may in turn influence pollutants exposure and accumulation (Molbert et al., 2020)

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First, the distinction between acute and chronic PIPN in terms of recruitment, animal models, and assessment methods is needed, where the majority of clinical and animal studies focused on the chronic PIPN as a dose-limiting toxicity