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GH therapy leads to a significant reduction in total fat mass, particularly in the abdominal region (Johannsson et al., Journal of Clinical Endocrinology & Metabolism )

The trial duration of the trials was from 16 to 104 weeks

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Therefore, large-scale, long-term, multi-center clinical trials and the establishing of a standardized quality control method were still needed to evaluate the safety and efficacy of BBR and BBR derivatives in treatment

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10.1161/ATVBAHA.108.162073 Summary Keywords DPP-4, DPP-4i, GLP-1, inflammation, cardiovascular effects, hypertension Citation Zhang J, Chen Q, Zhong J, Liu C, Zheng B and Gong Q (2019) DPP-4 Inhibitors as Potential Candidates for Antihypertensive Therapy: Improving Vascular Inflammation and Assisting the Action of Traditional Antihypertensive Drugs