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WADA Prohibition The World Anti-Doping Agency classifies both peptides as prohibited substances: Both listed under Section S0 (Non-Approved Substances) Prohibited at all times (in and out of competition) No Therapeutic Use Exemptions (TUEs) available for either peptide Detection methods under development for anti-doping testing TB-500 and thymosin beta-4 explicitly banned since 2011 WADAs position reflects that neither peptide has regulatory approval from any health authority worldwide

Singh highlighted two 2025 studies: one found GLP-1 use was associated with a lower incidence of progression to advanced AMD, including neovascular AMD and geographic atrophy, while another reported an increased risk of neovascular AMD among GLP-1 users

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