If 2 mg produced fewer side effects than 4 mg, then 0.5 mg should produce even fewer side effects than 2 mg
Low dose (1-2mg weekly) At the lowest effective doses, side effects are typically mild
Phase High escalation Weeks Weeks 13-16 Weekly Dose 6 mg Notes Phase 3 added this intermediate step
Glucagon normally signals the liver to release glucose and increases metabolic rate
The central GLP-1: implications for food and drug reward
The most common side effects of tirzepatide include: nausea, diarrhea, vomiting, constipation, stomach (abdominal) pain, indigestion, injection site reactions, feeling tired, allergic reactions, belching, hair loss, and heartburn