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doi: 10.1155/2013/348546

This assembly occurs in Cajal bodies nuclear structures that serve as assembly sites for ribonucleoprotein complexes before the holoenzyme is trafficked to telomeres

B12 injections are used to treat pernicious anemia, but high doses of vitamin B12 can cause serious side effects, including: blood clots, heart failure, low potassium, and fluid buildup in the lungs

Evidence position Predominantly laboratory and animal research, with very limited human data

Liposomes are formed in various sizes and with varying compositions and surface properties

Why Joint Aches Occur with B12 Supplementation When joint discomfort does arise in temporal association with vitamin B12 therapy, several possible explanations may be considered, though none represent a direct toxic or pharmacological effect of cobalamin itself