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Hepatitis C virus core protein induces hepatic steatosis in transgenic mice

While the safety profiles appear favorable (no serious adverse events reported across thousands of subjects), this does not carry the same weight as formal safety studies conducted under regulatory oversight

The vial should be stored in a cool dark area, not in direct sunlight

The SURMOUNT-1 trial protocol allowed one dose de-escalation for intolerable side effects, which underscores that slower titration is acceptable and sometimes preferred