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People with GI conditions (such as chronic diarrhea, celiac disease, Crohn's disease, and ulcerative colitis) or who have had procedures like gastric bypass surgery that impair nutrient absorption are also at greater risk

In a membrane-based system, the feed water is always at a higher pressure than the product water, and a loss of integrity in any membrane system or the EDI will negatively affect the water quality

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[3] Topiramate is excreted in human breast milk