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Cost Considerations Brand-name dual agonists (Mounjaro/Zepbound) cost $1,069 monthly compared to $969 to $1,349 for pure GLP-1 agonists (Ozempic/Wegovy)

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About 120 adults with progressive MS, clinically stable on existing therapy for at least a year with no relapses or new MRI lesions, will be randomized to weekly subcutaneous pegsebrenatide or placebo for 96 weeks