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However, further studies are needed to be conducted to clarify the effects of different doses, protocols, routes, and forms of LC on testicular functionality, semen quality, and molecular basics of how LC affects TBF in rams in adverse conditions

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Endocrinology 142 , 42444250 (2001)

The findings of another prospective study (the Hordaland Health Study) that followed 7,045 healthy adults (ages, 47-49 years and 71-74 years) suggested that high choline and low betaine plasma concentrations were associated with an unfavorable cardiovascular risk profile (51)