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Vegans and vegetarians should supplement with B12 to avoid the negative consequences of deficiency

The electrolyte-muscle connection is well established: cramps most often occur when the electrochemical environment inside muscle cells is disrupted

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Cleavage of SDF-1 by DPP-4 results in loss of activity (65), and consistent with this, DPP-4 inhibition in humans has been associated with enhancement of some effects which are associated with SDF-1 [increased levels of circulating endothelial progenitor cells (66) and increased distal tube sodium excretion (64)]

The specific aims were, firstly, to examine the use of vitamin B12 injections in all the Leicestershire practices

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