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Yugueros Gonzalez A, Kanter J, Sancho A et al

This effect is partly attributed to weight loss, a known mechanism for lowering blood pressure, so it is not surprising that this is part of the mechanism for GLP-1 RAs blood pressure reduction [36, 37]

While much of this is due to weight loss, the gut-mediated component is increasingly recognized

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Niacin (vitamin B3) is included for its essential role in energy metabolism, helping to reduce tiredness and fatigue while supporting normal nervous system function and mental performance