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Other post-translational regulators including Casein kinase II (CKII), PI3-kinase (PI3K), and c-Jun N-terminal kinases (JNKs) have also been implicated in modifying the cellular circadian clock, and may be critical for precise control of cellular circadian rhythms

Underlying conditions: digestive disorders like Crohn's or celiac disease, or autoimmune conditions, can cause you to use up B12 faster and may call for more frequent injections

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