First, the voluntary nature of FAERS reporting inevitably results in reporting and notoriety bias, as well as missing information, such as comorbidity and drug combination, which have been confirmed as crucial factors in severe outcomes ( Conclusion In summary, this research investigated the association between HE and commonly prescribed AEDs, with a particular emphasis on their use as monotherapy and in conjunction with VPA
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Zhao H, Ye L, Wang Y, Zhou X, Yang J, Wang J, Cao K,Zou Z
Dosing Miscalculations and Receptor Threshold Failures Melanotan-2 requires a minimum effective dose to saturate melanocortin receptors and trigger downstream signalling
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