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Model Selection: In vitro: 3T3-L1 adipocytes, primary adipocytes Ex vivo: Adipose tissue explants In vivo: DIO models, body composition assessment 5

Beef is an optimal source of B12 and provides the highest amount of this vitamin when grilled or roasted, since frying beef is shown to deplete some of its nutritional value

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In many cases, these deficiencies can be corrected by receiving regular injections of the missing vitamin

What has not changed is the underlying evidence base

Body composition beyond the scale Weight loss is the headline metric, but body composition changes matter more for long-term health