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Sterility & Endotoxin Testing: Vials undergo rigorous filtration and testing to ensure they are free from bacterial contaminants or pyrogens that could interfere with biological assays

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It is also a knowledge gap

These follow-on patents form a systematic attempt to add barriers of entry for generic competitors, with the intention of extending Novo Nordisks market monopoly for as long as possible when the main compound patent on the underlying active ingredient, semaglutide, expires

Al-Aly thinks that might be an underestimate because even though the study followed huge numbers of people, it covered only about four years, so they might have seen more Alzheimers cases if the study had gone on for longer, which might have translated to a larger benefit