Different host-tissue microenvironments select for cancer cells with distinct metastatic traits, which gives rise to organ-specific populations of metastatic cells [14]
In many disease models, such as those representing joints, metabolic organs, or immune niches, replicating in vivo -like crosstalk requires the co-culture of distinct patient-derived cells, including epithelial, stromal, immune, and vascular components
A vitamin B12 deficiency can cause a wide range of severe symptoms, such as fatigue, depression, nerve damage, muscle weakness, joint pain and difficulties with balance
Lattice compression increases the activation barrier for phase segregation in mixed-halide perovskites
Once sarin binds to cholinesterase the chemical stability of it's interaction with the enzyme can become irreversible with time due to the loss of an alkyl group
Montoya D, Mehta M, Ferguson BG, Teles RMB, Krutzik SR, Cruz D, Pellegrini M, Modlin RL, "Plasticity of antimicrobial and phagocytic programs in human macrophages", Immunology 156 (2): 164-173 (2019)