Lactate was originally thought to be transported into mitochondria primarily via the actions of the MCT1 transporter
a set of mental skills that help people manage everyday tasks and solve problems requiring planning, flexibility in thinking and self-control (assessed by the Tower of London task) (F = 4.504, p = 0.015)
In fact, thiamine levels may be reduced by 7576% in people with type 1 and type 2 diabetes ( People with alcoholism are also at an increased risk for deficiency because of a poor diet and impaired thiamine absorption ( Serious deficiency may lead to disorders known as beriberi and Wernicke-Korsakoff syndrome
Furthermore, the most common side effects of statins are headache, difficulty sleeping, flushing of the skin, drowsiness, dizziness, nausea or vomiting, abdominal cramping or pain, bloating or gas, diarrhea, constipation, and rare things are rhabdomyolysis, necrotizing autoimmune myopathy and liver toxicity
But you have to understand that, when it comes specifically to GLP-1 drugs, things get a bit more nuanced
Available from: Mafham M, Preiss D
