La eventual accin benfica de la liraglutida en el riesgo cardiovascular en pacientes con DM2 est siendo investigado en el estudio LEADER (Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results) 64
Patients with known liver disease, history of gastrointestinal bleeding, or those taking anticoagulant or antiplatelet medications face higher risk for significant bleeding complications and should have a lower threshold for seeking emergency care
Clarity on coverage means peace of mind and better planning
Kannt A, Pfenninger A, Teichert L, Tnjes A, Dietrich A, Schn MR, Klting N, Blher M. Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance. Diabetologia. 2015 Apr;58(4):799-808. doi: 10.1007/s00125-014-3490-7. Epub 2015 Jan 18. PMID: 25596852; PMCID: PMC4351435
These atypical patterns may warrant dose adjustment, temporary pause, or evaluation for unrelated conditions
Annual Review of Public Health. 2007;28:303-320
