GLP-1s like Wegovy and Mounjaro have four mechanisms to improve blood sugar levels and support weight loss: Improve insulin function: Improving insulin response to glucose from meals enables the body to move glucose from the blood and into the cells (like muscle cells) to be burnt for energy or stored as glycogen
The sleep apnea coverage is huge for a lot of people, says Bigham Steele
A substance sold outside regulated pathways may not match the drug studied in clinical trials, and it may lack appropriate quality controls or medical oversight
Subsequent meta-analyses of cardiovascular outcomes trials with GLP-1RAs have clearly excluded a causal role for GLP-1RAs in acute pancreatitis (63, 69, 70), while therapy with inhibitors of dipeptidyl peptidase-4 may lead to a minor elevation of this risk (69)
Still others say its about large companies keeping more profit- this makes little sense to me since only short-listed meds are permitted to be compounded- well, short-listed, like certain biologics
So I think this is going to wind up being a blessing in the end