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Several more recent studies reported large f/f 0 values for several IDPs, such as nucleoporin (Denning et al., 2003), securin (Snchez-Puig et al., 2005), plasmid partition protein KorB (Rajasekar et al., 2010), and neuroligin (Paz et al., 2008), for which the corresponding f/f 0 values were 2.8, 2.1, 1.9, and 1.6, respectively
The use of MOTs-C as a companion to GLP-1s, to prevent muscle loss, might get around this shortcoming of GLP-1s, but rigorous research is needed to prove [its effectiveness]
New England Journal Of Medicine *In a 68-week placebo-controlled study of 1,961 obese and overweight non-diabetic adults with weight-related conditions, those on semaglutide lost on average 14.9% of their weight as opposed to 2% of the placebo group
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