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Activa los genes implicados en la reparacin del ADN, la respuesta al estrs, la remodelacin matricial y las defensas antioxidantes, al mismo tiempo que reprime los genes asociados a la inflamacin, la fibrosis y la destruccin tisular

doi: 10.1038/s41590-022-01355-3 57 KarasawaTKawashimaAUsui-KawanishiFWatanabeSKimuraHKamataRet al

Psoralen (PSR) in conjunction with ultraviolet A (PUVA) treats vitiligo, a depigmenting skin condition, by promoting both tyrosinase activity and melanin production in melanocytes

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Monitoring IGF-1 baseline before starting, then mid-cycle (week 6-8) and 4 weeks post-cycle

Epigenetic modifications in cutaneous malignant melanoma: EZH2, H3K4me2, and H3K27me3 immunohistochemical expression is enhanced at the invasion front of the tumor