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This variation depends on skin sensitivity, injection depth, needle speed, and individual pain perception

Food stays in your stomach longer, which maintains the feeling of fullness between meals and can cause the nausea that most users experience during dose escalation

However, if nausea persists beyond week 6 or is so severe you can't eat enough protein, talk to your provider about a slower dose escalation or an anti-nausea strategy

Handa, A

Key Insights from 20182022 In 2022, compared to patients receiving semaglutide onlabel, those receiving it offlabel were: 45.7 vs