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Macrophage Polarization Your immune system contains macrophages that can either promote inflammation (M1 type) or support tissue repair (M2 type)

1 Introduction 1.1 Literature review methodology This review was conducted by searching PubMed, Scopus, and Google Scholar databases using the keywords Parkinsons disease, -synuclein, dopaminergic neurons, LRRK2, mitochondrial dysfunction, comorbidities, levodopa, and neuroinflammation. Studies published in English between 2000 and 2025 were included

Such damage can further lead to mitochondrial dysfunction, triggering apoptosis or necroptosis, which represents a key pathological process in oxidative stress [61]

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Skin Brightness and Antioxidant Support IV Glutathione delivers concentrated antioxidant support directly to the bloodstream, where it can reach tissues more effectively than topical or oral options

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