However, there are some challenges in understanding the impact on body composition and the durability of the achieved weight loss
In order to avoid hypoglycemia in patients on insulin a reduction in insulin dose may be considered, particularly in patients with good glycemic control
In the study, participants with a responsive genetic score had an 82% increase in the likelihood of acheiving weight loss with a GLP-1 medication.[ref] Another study showed that GLP1 receptor variants are associated with greater weight loss on GLP-1 RA drugs.[ref] Common genetic variants in the GLP1R (GLP-1 receptor) gene impact weight and type 2 diabetes risk
Theyre also, for the most part, temporary as you adjust to the medication
[DOI] [PubMed] [Google Scholar] 64.Simpson KW, Fyfe J, Cornetta A
Prostate Cancer Prostatic Dis 2024;28:370377