Unfortunately, the degradation of function that accompanies fibrotic changes is difficult to treat
SASP factors mediate chronic inflammation, activate cardiac fibroblasts, and exacerbate cellular senescence and tissue damage (Mehdizadeh et al., 2022)
All but BMI were within normal range ( Table 2 ), which excludes frequent conditions that may independently cause fatigue (insufficient levothyroxine dose, anemia, diabetes with poor glycemic control, infection)
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