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Phase Maintenance Weeks 25+ Tirzepatide 15.0 mg/week Cagrilintide 2.4 mg/week Notes Full 3-receptor coverage if tolerated

Expected timeline: Week 1-4: Inflammation reduction, potential nerve symptom improvement Week 4-8: Progressive healing, reduced radicular symptoms Week 8-12: Structural improvements developing, continued symptom reduction Week 12-16: Consolidation of gains, assessment for continued protocol Important notes: Disc herniations vary enormously in severity

doi: 10.1007/s40264-020-00953-0 46 MukhtarI.AnwarH.HussainG.RasulA.NaqviS