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This leads to an imbalance in the glutathione/reactive oxygen species (ROS) axis and enhanced pyrimidine biosynthesis, which in turn sustains the cancer stem cell-like properties of lung cancer cells and drives the malignant progression of NSCLC ( Metabolites involved in the serine/glycine pathway are markedly depleted in the plasma of NSCLC patients after radiotherapy and in corresponding cellular models, indicating that tumor cells utilize these metabolites to facilitate DNA damage repair and cell survival

Saline, GYY4137 (200 M),and Oral HS lipo (200 M) were administered once daily via oral gavage ( Fig

In Germany, scientists realized that the rats barely respond to heat-based pain on their skin, including that caused by acid

Xiao, M

Baran R, Stroud JD

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