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By binding to GLP-1 receptors in the brain, particularly in areas responsible for controlling appetite and food intake, semaglutide helps manage weight through several key mechanisms

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Previous studies have shown that GLP-1RAs may contribute to the stabilization of atherosclerotic plaques through the promotion of nitric oxide (NO) production, anti-inflammatory effects, inhibition of macrophage activity, reduction of oxidative stress, and improvement of lipid metabolism 12,13,14,15,16,17,18,19,20

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