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Name: why doesn't semaglutide work for me GLP-1 drugs while you're on them. The problem is what happens when you stop. Clinical trials show two-thirds of people regain the weight within a year of stopping — and How Does Semaglutide Work?- Jacksonville,
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They bind to specific receptors in the hypothalamus and pituitary gland, triggering pulsatile GH release

The markedly reduced risk here for alcohol use disorder patients taking GLP-1 agonists suggests that this class of drugs might actually be more effective than the current crop of officially approved medications for treating alcohol addiction