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One proposed solution is to administer dopamine directly to the brain, bypassing the need for its enzymatic conversion from levodopa

The good news is that this reaction is almost always a matter of chemistry and technique rather than a sign that anything has gone wrong

R., & Swisher, C

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The thiol side chain of cysteine often participates in enzymatic reactions such as a nuecleophile (a chemical species that donates an electron pair to an electrophile to form a chemical bond in relation to a reaction)

10.1371/journal.pone.0160620 186 PasseriE.ElkhouryK.MorsinkM.BroersenK.LinderM.TamayolA.et al (2022)