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It comes down to pharmacokinetics, individual biology, the specific medication being used, and a handful of factors that most providers never explain in detail

In addition, they can also extend feelings of fullness and curb unhealthy cravings by slowing down gastric emptying

Patients should be advised that initial shedding may occur in the first few weeks, and visible improvement typically takes 36 months of consistent use

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The key difference

Semaglutide 2.4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial