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Trimethoprim-sulfamethoxazole offers convenient 3-day treatment with 85-95% cure rates, but resistance rates exceed 20% in many areas, requiring local susceptibility data for optimal prescribing

Walraven and Hinz, 2018)

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In neurodegenerative diseases such as PD and AD, BBB dysfunction is a common pathological feature

Doing things like setting a consistent sleep/unwinding routine, practicing meditative exercises, limiting screens an hour before bed, getting some sunlight throughout the day, and more can have a big impact