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Moreover, the resistance of PLGA nanoparticles encapsulating DDA-GSH-AuNCs to photobleach upon continuous laser irradiation was evaluated in comparison with conventional fluorescent dyes: Nile red and fluorescein (relatively stable and labile dyes to photobleaching, respectively) 51

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Together with the electron-impact fragmentation pattern of each identified MCF derivatised 13 C-labelled metabolite, the degree of labelling was estimated based on the variation observed in the fragmentation pattern of 13 C-labelled metabolites in comparison to their counterpart 12 C mass spectrum